NMN vs Nicotinamide Riboside

An essential universal coenzyme named Nicotinamide Adenine Dinucleotide (NAD+) takes part in generating energy, maintaining genetic code integrity, and regulating many other life processes. The NAD+ levels start decreasing as we get older, and this causes health concerns. However, some potential precursors, such as nicotinamide mononucleotide and nicotinamide riboside (NMN/NR), have recently shown great interest. This blog post will examine NMN vs. Nicotinamide Riboside to determine which is better!

What are NMN and Nicotinamide Riboside

Before discussing “NMN vs. Nicotinamide Riboside,” we should know about these two terms!

What Is NMN? 

  • Definition and Chemical Structure: It is a nucleotide composed of ribose, nicotinamide, and phosphate groups, which serve as an intermediary in producing NAD+ within cells.
  • Sources and Availability: Natural sources include broccoli, avocados, and cabbage; however, they can also be purchased as dietary supplements.
  • Benefits and Effects on NAD+ Production: Supplementation with this compound has been associated with higher NAD+ levels in cells, aiding energy production, metabolism, and overall vitality – and being studied for potential anti-aging benefits.
  • Potential Delays and Side Effects: Though usually safe, supplementation with NMN may produce mild side effects, including stomach upset or flushing at higher doses.

What is Nicotinamide Riboside (NR)?

  • Definition and Structure: NR is an irreducible riboside form of vitamin B3, acting similarly to its precursor NMN as an essential precursor for NAD+ formation.
  • Sources and Availability: It is found naturally in milk and beer and sold as an anti-aging dietary supplement. It may offer potential anti-aging advantages when taken orally.
  • Benefits and Effects on NAD+ Production: NR supplements have been shown to boost levels of NAD+ in our bodies, offering support to mitochondrial function, energy production, and cell repair processes. They may hold potential against age-related health conditions like atherosclerosis.
  • Potential Drawbacks and Side Effects: While generally well tolerated, some high doses have reported rare side effects, including mild digestive disturbances and minor skin reactions.

NMN vs. Nicotinamide Riboside: Which is Better?

Comparison of Benefits and Drawbacks:

Both compounds offer similar benefits, including enhanced NAD+ production and potential anti-aging effects. NMN is directly converted into NAD+ in cells, while NR requires an additional step.

Discussion of Scientific Studies and Clinical Trials:

Scientific research supports the efficacy of both compounds in raising NAD+ levels. Various studies have explored their impacts on aging, metabolism, and overall health.

Potential Applications and Future Research:

NMN and NR are being investigated for their applications in age-related diseases, metabolic disorders, and neurodegenerative conditions. Ongoing research may unveil new therapeutic potentials.


NMN vs. Nicotinamide Riboside – Both serve as valuable precursors to NAD+, offering potential benefits in cellular health, metabolism, and longevity. Their availability as supplements allows individuals to support their well-being actively.

When considering NMN or NR supplementation, it is essential to consult healthcare professionals, especially if you have underlying health conditions or are on medications. At UltraHealh, making informed decisions guided by scientific understanding and professional advice empowers individuals to navigate the realm of NAD+ precursors, unlocking the potential for enhanced cellular vitality and a healthier, more energetic life!

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